PUBLICATION

Aberrant DNA methylation of Tgfb1 in diabetic kidney mesangial cells

Shigeyoshi Oba, Nobuhiro Ayuzawa, Mitsuhiro Nishimoto, Wakako Kawarazaki, Kohei Ueda, Daigoro Hirohama, Fumiko Kawakami-Mori, Tatsuo Shimosawa, Takeshi Marumo, Toshiro Fujita

Scientific reports 8 (1), 1-16, 2018

Aberrant DNA methylation of hypothalamic angiotensin receptor in prenatal programmed hypertension

Fumiko Kawakami-Mori, Mitsuhiro Nishimoto, Latapati Reheman, Wakako Kawarazaki, Nobuhiro Ayuzawa, Kohei Ueda, Daigoro Hirohama, Daisuke Kohno, Shigeyoshi Oba, Tatsuo Shimosawa, Takeshi Marumo, Toshiro Fujita

JCI insight 3 (21), 2018

Aberrant DNA methylation of pregnane X receptor underlies metabolic gene alterations in the diabetic kidney

Atsushi Watanabe, Takeshi Marumo, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Kohei Ueda, Daigoro Hirohama, Toshiya Tanaka, Shintaro Yagi, Satoshi Ota, Genta Nagae, Hiroyuki Aburatani, Hiroo Kumagai, Toshiro Fujita

American Journal of Physiology-Renal Physiology 314 (4), F551-560, 2018

Aldosterone is essential for angiotensin II-induced upregulation of pendrin

Daigoro Hirohama, Nobuhiro Ayuzawa, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Takeshi Marumo, Shigeru Shibata, Toshiro Fujita

Journal of the American Society of Nephrology 29 (1), 57-68, 2018

Renal Dysfunction Induced by Kidney-Specific Gene Deletion of Hsd11b2 as a Primary Cause of Salt-Dependent Hypertension

Kohei Ueda, Mitsuhiro Nishimoto, Daigoro Hirohama, Nobuhiro Ayuzawa, Wakako Kawarazaki, Atsushi Watanabe, Tatsuo Shimosawa, Johannes Loffing, Ming-Zhi Zhang, Takeshi Marumo, Toshiro Fujita

Hypertension 70 (1), 111-118, 2017

Rac1-mediated activation of mineralocorticoid receptor in pressure overload–induced cardiac injury

Nobuhiro Ayuzawa, Miki Nagase, Kohei Ueda, Mitsuhiro Nishimoto, Wakako Kawarazaki, Takeshi Marumo, Atsu Aiba, Takayuki Sakurai, Takayuki Shindo, Toshiro Fujita

Hypertension 67 (1), 99-106, 2016

Diabetes induces aberrant DNA methylation in the proximal tubules of the kidney

Takeshi Marumo, Shintaro Yagi, Wakako Kawarazaki, Mitsuhiro Nishimoto, Nobuhiro Ayuzawa, Atsushi Watanabe, Kohei Ueda, Junichi Hirahashi, Keiichi Hishikawa, Hiroyuki Sakurai, Kunio Shiota, Toshiro Fujita

Journal of the American Society of Nephrology 26 (10), 2388-2397, 2015

Immunomodulation with eicosapentaenoic acid supports the treatment of autoimmune small-vessel vasculitis

Junichi Hirahashi, Kimito Kawahata, Makoto Arita, Ryo Iwamoto, Keiichi Hishikawa, Mie Honda, Yoshifumi Hamasaki, Mototsugu Tanaka, Koshu Okubo, Miho Kurosawa, Osamu Takase, Masanori Nakakuki, Kan Saiga, Kazuo Suzuki, Shoji Kawachi, Akihiro Tojo, George Seki, Takeshi Marumo, Matsuhiko Hayashi, Toshiro Fujita

Scientific reports 4 (1), 1-11, 2014

Epigenetic modulation of the renal β-adrenergic–WNK4 pathway in salt-sensitive hypertension

ShengYu Mu, Tatsuo Shimosawa, Sayoko Ogura, Hong Wang, Yuzaburo Uetake, Fumiko Kawakami-Mori, Takeshi Marumo, Yutaka Yatomi, David S Geller, Hirotoshi Tanaka, Toshiro Fujita

Nature Medicine 17 (5), 573-580, 2011

Histone deacetylase modulates the proinflammatory and-fibrotic changes in tubulointerstitial injury

Takeshi Marumo, Keiichi Hishikawa, Masahiro Yoshikawa, Junichi Hirahashi, Shoji Kawachi, Toshiro Fujita

American Journal of Physiology-Renal Physiology 298 (1), F133-F141, 2010